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Glucagon-like Peptide-1 Receptor (GLP-1R) Signaling: Making the Case for a Functionally Gs Protein-Selective GPCR
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A) Sequences of peptides that activate the GLP‐1 receptor. (B)
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Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor
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Peptide-bound GLP-1R-Gs complexes active-state conformations (A and B)
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JCI
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Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein
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Frontiers
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