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GLP 1 receptor agonists should not be combined with DPP 4 inhibitors, as there is no added glucose lowering benefit beyond that of the GLP 1 RA alone. Both drug classes work through overlapping mechanisms involving Doer Biologics published paper of a long acting GLP 1R GCGR dual agonist for the treatment of diabetes and obesity GLP 1R Signaling and Functional Molecules in Incretin Therapy The impact of glucagon like peptide 1 receptor agonists in the patients undergoing anesthesia or sedation: systematic review and meta analysis Perioperative Medicine Springer Nature Link Pfizer Is Going All In on GLP 1 Drugs Through China