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Microdosing GLP 1 agonistsusing doses below FDA approved levels for T2D or obesityis rapidly gaining traction as an off label strategy to improve tolerability, tailor titration, and manage costs. Dan T. A lot of patients are asking why their face looks different after being on GLP 1 medications. The answer is simplewhen you lose weight, you also lose volume in the face. That can GLP 1s (incretin mimetics), This type of medication works by increasing the levels of hormones called incretins. These hormones help the body produce more insulin only when needed and reduce the GLP 1 receptor agonist versus DPP 4 inhibitor and kidney and cardiovascular outcomes in clinical practice in type 2 diabetes ScienceDirect GLP 1s May Cause Hair Thinning in the First Year But It's Likely Temporary