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glp-1 news november 2025 Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity November 5, 2025 DOI: 10.1056/NEJMdo008238 New for the treatment of obesity - and so many additional indications being studied

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Machine learning designs new GCGR GLP 1R dual agonists with enhanced biological potency Nature Chemistry Many people start and stop GLP 1s. Here's why that may be a bad idea : NPR Orforglipron Oral GLP 1: Clinical Progress and Insights GLP1 Receptor Agonists and Preclinical Assay Strategies Celtarys Glucagon like Peptide 1, Glucose Dependent Insulinotropic Polypeptide, and Glucagon Receptor Agonists in Metabolic Dysfunction Associated Steatotic Liver Disease: Novel Medication in New Liver Disease Nomenclature
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Melesio Bustamante
Battle Creek, US
★★★★★ 5
Favorite balls
Color: Multicolor, Size: 6 PACK
I never thought that my black lab mix could enjoy a ball more than the slightly larger silicon (sp) ones we have used for years. The sound has her ears up from the moment I pick one up. Please not, these are not indestructible. Throwing them away once they break open (for heavy chewers) is best.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 18, 2026
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Verified Purchase
TRT
Alexandria, US
★★★★★ 5
Dog loves these
Color: Multicolor, Size: 6 PACK
Perfect balls for dogs who chew the squeaker out. These have the felt going over the plastic squeaker piece. Super bright colors and perfect size for medium and small dogs.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 21, 2026
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Verified Purchase
dreamy
Grantham, US
★★★★★ 5
So far so good!
Color: Multicolor, Size: 24 PACK
So far so good! Our Belgian Malinois/Black Lab mix goes through other brands of squeaky tennis balls in a matter of days. Including the ones that cost 2.00 a piece. Thrilled to see that the first one is still intact after a couple of weeks of play. She must squeak them if they are in her mouth so they do get quite a workout. I would highly recommend them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 21, 2026
A
Verified Purchase
alethia
Omaha, US
★★★★★ 5
Nice
Color: Yellow, Size: 6 PACK
My puppy loves these but it stopped squeaking in like 5 min! He’s a big boy tho 🤷🏽‍♀️
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Reviewed in the United States on April 30, 2026
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Verified Purchase
Amiable
Natrona Heights, US
★★★★★ 4
Close to Perfect
First ball I picked out of the box the squeaky didn't work. 1 out of 24 not bad.
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Reviewed in the United States on March 2, 2026

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